Hutchinson's triad

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Hutchinson's triad is named after Sir Jonathan Hutchinson (1828–1913). It is a common pattern of presentation for late congenital syphilis, and consists of three phenomena: interstitial keratitis, malformed teeth (Hutchinson incisors), and eighth nerve deafness. There may also be a deformity on the nose known as saddle nose deformity.[1][2]

Interstitial keratitis is usually seen between five and twenty years of age. Damage to the teeth occurs in the first weeks after birth but is not seen until the first permanent teeth erupt around six years old. Eighth nerve deafness typically starts with high-frequency hearing loss between eight and ten years old, but can start at a younger age.[3]

References[edit]

  1. ^ Singh, Ameeta E.; Barbara Romanowski (1 April 1999). "Syphilis: Review with Emphasis on Clinical, Epidemiologic, and Some Biologic Features". Clinical Microbiology Reviews. 12 (2): 187–209. doi:10.1128/CMR.12.2.187. PMC 88914. PMID 10194456.
  2. ^ Pessoa, L.; Galvão, V. (2011). "Clinical aspects of congenital syphilis with Hutchinson's triad". BMJ Case Reports. 2011: bcr1120115130. doi:10.1136/bcr.11.2011.5130. PMC 3246168. PMID 22670010.
  3. ^ Pessoa, Larissa; Galvão, Virgilio (2011). "Clinical aspects of congenital syphilis with Hutchinson's triad". Case Reports. 2011: bcr1120115130. doi:10.1136/bcr.11.2011.5130.